"In The BMJ's Christmas edition this week, a study identifies the genetic origin of the ability to smell the strong, characteristic odor in human urine produced after eating asparagus.
...Asparagus is considered a delicacy, but it's also known to produce a distinctive odor in urine.
Not everyone can detect the odour of metabolites (methanethiol and S-methyl thioesters) produced by consumption of asparagus.
...Findings show that 40% (2,748/6,909) of participants agreed that they could smell a distinct odor in their urine after eating asparagus, and 60% (4,161/6,909) said they could not and were labelled as 'asparagus anosmic'.
The researchers linked information from genome wide association studies on over 9 million genetic variants with the asparagus anosmia trait.
They discovered 871 particular variations in DNA sequence, known as single nucleotide polymorphisms, on chromosome 1 which were associated with being asparagus anosmic. These genetic variants were found in several different genes responsible for sense of smell.
They also found that a higher proportion of women reported they were unable to detect the odor, compared to men, despite women being known to more accurately and consistently identify smells..."
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