I love this:
Testosterone’s reputation has had its ups and downs since the hormone was first synthesized in the 1930s... Despite the presumed risks, he says he still thought that the hormone could help some of his patients who had low testosterone and sexual problems. So, he started treating them while monitoring them closely.
They didn’t get cancer, Morgentaler says, and they benefited from the treatment greatly. Some of his clinical findings — along with the revelation that Huggins’s most dire warnings about the hormone causing cancer were based on observations of a single person — helped to clear the way for renewed interest in testosterone therapy.
Sample size: One.
So much received medical wisdom comes from this sort of thing. - Glenn Reynolds
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